CD28 (CD28 Molecule) is a Protein Coding gene. Diseases associated with CD28 include Classic Mycosis Fungoides and Sezary's Disease. Among its related pathways are CD28 co-stimulation and PI5P, PP2A, and IER3 Regulate PI3K/AKT Signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding and obsolete SH3/SH2 adaptor activity. An important paralog of this gene is CTLA4. Involved in T-cell activation, cell proliferation cytokine production induction, and promoting T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells.
Our biosimilar antibodies are carefully designed for research, ensuring reliability and effectiveness. Available in small or large quantities, they are ideal for research and commercial applications.