The CALCA gene encodes peptide hormones calcitonin, calcitonin gene-related peptides, and calmodulin through tissue-specific selective RNA splicing of gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and regulates phosphorus metabolism. CALCB (calcitonin related peptide beta) is a protein coding gene. Diseases related to CALCB include medullary thyroid carcinoma and immunodeficiency 53. Its related pathways include downstream signaling of GPCRs and presynaptic function of Kainate receptors.
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