CD28 (CD28 Molecule) is a Protein Coding gene. Diseases associated with CD28 include Classic Mycosis Fungoides and Sezary's Disease. Among its related pathways are CD28 co-stimulation and PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding and obsolete SH3/SH2 adaptor activity. An important paralog of this gene is CTLA4.Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells.
Alpha Lifetech can provide Recombinant Protein products. Including various specifications such as 50, 100, and 500ug, this protein product has been purified and passed quality inspection. Scientists from all over the world are welcome to consult