SIRPA (Signal Regulatory Protein Alpha) is a Protein Coding gene. Diseases associated with SIRPA include Hyperglycemia and Glioblastoma. Among its related pathways are Innate Immune System and Cell junction organization. Gene Ontology (GO) annotations related to this gene include SH3 domain binding. An important paralog of this gene is SIRPB1.Immunoglobulin-like cell surface receptor for CD47.
Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane.
Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment.
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